Who can be affected by IgA Nephropathy?

How common is IgA Nephropathy?

IgA Nephropathy is a rare disease, but the most common form of glomerulonephritis. The worldwide incidence is estimated to be at least 2.5 cases per 100,000 of the population.1 Prevalence varies by geographical region and ethnic origin. Although there are no standardised international biopsy guidelines, biopsy and dialysis registers show that the incidence rates of IgA Nephropathy tend to be higher in Asiatic countries.2 

Annually reported new cases of IgAN worldwide

2,5/100.000

individuals worldwide develop IgAN every year.1

Learn more about the worldwide prevalence of IgA Nephropathy.*

Learn more about the worldwide prevalence of IgA nephropathy.*
1

Europe

22% 

2

USA

12% 

3

Latin America

6% 

4

Asia

40 % 

* Frequency of cases of IgAN among glomerular diseases diagnosed by means of biopsy. Adapted from:  O’Shaughnessy MM et al. (2018).3

Is everybody equally at risk of developing IgAN?

Individuals of any age can develop IgA Nephropathy. However, this form of glomerulonephritis occurs most frequently in persons in their late teens to their late 30s. Men are at greater risk of developing IgAN; statistics show that they suffer from the disease on average twice as frequently as women.3, 4

Age groups in which IgAN tends to be most common

Persons aged 16-35 years

is the age group in which IgAN occurs most frequently 5, 6

Distribution of cases of IgAN by gender

~ 2 ×

more men than women develop IgAN.3

Learn more about IgAN

What is IgAN?

What is IgAN?

Gain initial insights into IgA Nephropathy, its main symptoms, its progression and its effects on the kidneys. You will be surprised at the complexity of the disease!

Clinical course

Clinical course

Obtain an overview of the stages of IgA Nephropathy and how the disease is manifested. Click here to learn more about the characteristic progression of the disease and those factors that can exacerbate it.

What is the impact of IgAN?

What is the impact of IgAN?

Are you aware what impact living with IgA Nephropathy can have on the daily life of those affected? Learn about the emotional and psychosocial consequences of this Nephropathy.

Referenzen

  1. McGrogan A et al. The incidence of primary glomerulonephritis worldwide: a systematic review of the literature. Nephrol Dial Transplant 2011; 26(2): 414–430.
  2. Rodrigues JC, Haas M, Reich HN. IgA Nephropathy. Clin J Am Soc Nephrol 2017; 12(4): 677–686. 
  3. O’Shaughnessy MM et al. Glomerular disease frequencies by race, sex and region: results from the International Kidney Biopsy Survey. Nephrol Dial Tranplant 2018; 33(4): 661–669.
  4. National Institute of Diabetes and Digestive and Kidney Diseases. IgA Nephropathy, under: Https://www.niddk.nih.gov/health-information/kidney-disease/iga-nephropathy (last accessed: February 2022).
  5. Thaiss F, Stahl RAK. IgA-Nephropathie. Klinik, Pathogenese und Therapie der häufigsten Glomerulonephritis. Dt Ärztebl 2000; 97(41): A 2708–2711.
  6. Medscape.com. Pediatric IgA Nephropathy, under: https://emedicine.medscape.com/article/981516-overview (last accessed: February 2022).